Antibacterial activity of plant asparagus racemosus of. The aim of this study was to investigate the effect of ethanolic extract of asparagus racemosus on urolithiasis in rats. The relationship between antioxidant and antiulcer. A herbal synergistic formulation for treatment of acute and chronic ulcers in the stomach. Crude extract also significantly reduced volume of gastric secretion, free. Ulcer was induced by the indomethacin nsaid and swim restraint stress treatment. Pdf preclinical screening of antiulcer activity of asparagus.
Plant profile, phytochemistry and pharmacology of asparagus. Phytochemical screening and antioxidant properties of. Antiulcer potential of the ethanolic extract of aerva persica merrill root in rats. The results of their study suggested that asparagus racemosus causes an inhibitory effect on release of gastric hydrochloric acid and protects gastric mucosal damage. In vivo evaluations were done by ccl4 induced hepatotoxicity. The antiulcer activities of the ethanolic extract of this root could be attributed to its flavonoids and tannins. The present study examined the antioxidant activity and protective effect of extracts from asparagus racemosus roots against lipofectamineinduced apoptosis. An official publication of the indian pharmacological society. Annals of the new york academy of sciences, 1056, 261 278. Hence, the present work was undertaken to evaluate its. Study of antiurolithiatic activity of asparagus racemosus. Indomethacin plus plinduced gastric ulceration model was used in. Antiulcer, asparagus racemosus, phenylbutazone, plant extract. Bhupesh kumar vema, alok mukerjee, amita verma, shanti bhushan mishra and alka verma.
Various studies have indicated immunomodulatory properties of shatavari root extracts and formulations. Recent studies on shatavari shatavari,asparagus racemosa. Plant profile, phytochemistry and pharmacology of sparagus. Glcnactransferase in cell free assays and recently to exhibit immunomodulation activity against specifict. Saponins have surfactant property, inhibits gastric acid secretion, and. On the basis of these reports, this study has been undertaken to study the antiurolithiatic activity of ethanolic extract of a. Environmental issues antioxidants antioxidants nutrients aspirin famotidine licorice plant health aspects ulcers care and treatment methods. Implications for immunoadjuvant potential author links open overlay panel manish gautam a santanu saha a sarang bani b 1 a. Asparagus racemosus herb uses, benefits, cures, side. Preclinical screening of antiulcer activity of asparagus racemosus extract on phenylbutazone induced ulceration in experimental animals. We have highlighted some of the important plants reported for their antiulcer and ulcer healing properties, in our. Antiulcer activity of methanol extract of erythrina indica.
This plant possesses a wide range of secondary metabolites inclusive of steroids, alkaloids, dihydrophenanthrene derivatives, flavonoids, furan. Antisecretory and antiulcer activity efficacy of a. The gastric ulcer reduction was also comparable to the standard antiulcer drug ranitidine given at the dose. Reports indicate that the pharmacological activities of asparagus racemosus root extract include antiulcer 4, antioxidant, antidiarrhoeal, antidiabetic. To investigate the antioxidant activities of asparagus racemosus root extracts via total phenolic and. Phytochemical screening of methanolic extract of asparagus racemosus. Groups of six animals each were pretreated with 50% ethanolic extract of asparagus racemosus 30 minutes before the ulcerogenic procedure in the following manner. It is of great therapeutic value in treating diseases such as, typhoid, piles, inflammation, asthma, bronchitis, and dysentry. Asparagus racemosus was found to be an effective anti ulcerogeni c agent, whose activity can well be compared with that of ranitidine hydrochloride 10. Assessment of the antiulcer potential of moringa oleifera. Groups of six animals each were pretreated with 50% ethanolic extract of asparagus racemosus 30 minutes before the ulcerogenic procedure in. Preclinical screening of antiulcer activity of asparagus racemosus extract on phenylbutazone induced ulceration in experimental animals bhupesh kumar vema, alok mukerjee, amita verma, shanti bhushan mishra and alka verma abstract the present study aimed to evaluate the effect of 50% ethanolic extract of asparagus racemosus whole.
Antidepressant activity of asparagus racemosus in rodent. Pharmacological evaluation for antidepressantlike activity of asparagus racemosus willd. The ulcer protective effect of methanolic extract of fresh roots of a. Desmodium gangeticum dc leguminosae, popularly known as shaparni in hindi, is a wellknown indian medicinal plant. Antihyperglycaemic activity of asparagus racemosus roots is partly mediated by inhibition of carbohydrate digestion and absorption, and enhancement of cellular insulin action volume 107 issue 9 j. However, there is no scientific proof justifying the traditional use of asparagus racemosus root in the treatment of. Protective effects of asparagusracemosus on oxidative damage. Antiulcer and antioxidant activity of asparagus racemosus. The therapeutic applications of this plant have been reported in indian and british pharmacopoeias and in traditional system of medicine, such as ayurveda, unani and siddha. Thirtysix male wistar albino rats were randomly divided into six groups n 6. In silico study, plant metabolites showed interaction between protodioscin secondary metabolites of asparagus racemosus and interferon. Antihyperglycaemic activity of asparagus racemosus roots. Prakash, 1 and ramachandran sundaram 1 rajiv gandhi university of health sciences, 4 th t block, jayanagar, bangalore, karnataka, india.
Antiulcer and antioxidant activity of asparagus racemosus willd and withania somnifera dunal in rats. A study of ancient classical ayurvedic literature claimed several therapeutic attributes for the root of a. Antioxidant property of the root of asparagus gonoclados. Asparagus racemosus is a plant traditionaly used in epilepsy, as a brain tonic, cardiac disorders, hypertension, habitual abortions, weakness of the uterus, excessive bleeding during menstruation. Pylorus ligation was performed in all groups of rats for the induc. Study of antiurolithiatic activity of asparagus racemosus on albino rats. This site is like a library, you could find million book here by using search box in the header. Immunomodulatory active steroidal saponins from asparagus. Immunomodulatory activity of asparagus racemosus on systemic th1th2 immunity. Bhatnagar m, sisodia ss, 2006, antisecretory and antiulcer activity of asparagus racemosus wild, against indomethacin plus phyloric ligationinduced ga stric ulcer in rats. Peptic ulcer is a deep gastrointestinal erosion disorder that involves the entire mucosal thickness and can even penetrate the muscular mucosa. The different parameters of observation were piloerection, salivation, increase in motor activity, irritability, reactivity, jumping squeaking, and aggressive fighting. Jan 22, 2006 comparative study of the antiulcer and antisecretory activity of asparagus racemosus willd shatawari and withania somnifera dunal ashwagandha root extract with a standard drug, ranitidine, in various models of gastric ulcer in rats is presented. Biochemical activity and mode of action of asparagus racemosus 9, 14, 26, 20, 14, 25, 18 bio activity of a.
Summary the present study was undertaken to investigate the effect of asparagus racemosus. Asparagus racemosus due to its slow growth faces lots of problem which can be solved through tissue culture. The antioxidant activities of methanolic extract of a. Antiulcer activity of methanol extract of erythrina indica lam. The roots are said to be tonic and diuretic and galactgogue, the drug has ulcer healing effect probably via strenthening the mucosal resistance or cytoprotection.
Antiulcer effect ulcer is one of the burning problems in. Antioxidant activities of ethanolic and aqueous extracts. Immunological activity the use of asparagus racemosus dried root powder modulates the activity of immune system. Antibacterial activity of plant asparagus racemosus belonging to family liliaceae,was evaluated some selected human pathogenic microorganism pseudomonas aeroginosa,escherichia coli, staphylococcus aureus following agar well diffusion method using different concentration 60%, 80%, 100%. Asparagus racemosus is an ayurvedic rasayana, which finds mention in ancient indian texts for treatment of gastric ulcers. Antiulcer activity of aqueous and ethanolic extracts of glycyrrhiza glabra l. Azadirachta indica, hemidesmus racemosus, asparagus racemosus, and musa sapientum. Antioxidant activity and antiapoptotic effect of asparagus. Formulations comprise plant extracts together with conventional additives to form the oral dosage forms which include tablets, capsules and powders ready for suspension.
Asparagus racemosus shatawari, phytoconstituents and medicinal importance, future source of economy by cultivation in uttrakhand. Asparagus racemosus was found to be an effective antiulcerogenic agent, whose activity can well be compared with that of ranitidine hydrochloride. Reports indicate that the pharmacological activities of root extracts include antiulcer 8, antitussive 9, antioxidant 10 and antibacterial activities 11. Stages of activity and aggressive behavior were recorded live every 10 min for 30 min after ldopa administration by the blind observer. Immunomodulatory activity of asparagus racemosus on. Gastroduodenal ulcer protective activity of asparagus. Antiulcer potential of the ethanolic extract of aerva. Preclinical screening of antiulcer activity of asparagus racemosus. Shatavarins containing shatavarin iv with anticancer. A large number of populations are now relying on these medicinal plants as they are relatively safe, cheap and have no adverse effects.
Preclinical screening of antiulcer activity of asparagus. Roots of asparagus racemosus willd shatavari in vernacular are widely used in ayurveda as rasayana for immunostimulation, galactogogue as also in treatment of conditions like ulcers and cancer. Leaves in experimental animals s sakat sachin, r juvekar archana department of pharmaceutical sciences and technology, institute of chemical technology, nathalal parikh marg, matunga e, mumbai400019, m. Apr, 2012 read immunomodulatory active steroidal saponins from asparagus racemosus, medicinal chemistry research on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Study of antiurolithiatic activity of asparagus racemosus on. Jangle department of biochemistry, rural medical college, pravara institute of medical sciences, loni, ahmednagar, maharashtra, india. Antioxidant activity dpph free radical scavenging activity this assay is based on scavenging of the dpph radical from the antioxidants, which produces a decrease in absorbance at 517 nm. The results of this study suggest that asparagus racemosus causes an inhibitory effect on release of gastric hydrochloric acid and protects gastric mucosal damage. Comparative study of the antiulcer and antisecretory activity of asparagus racemosus willd shatawari and withania somnifera dunal ashwagandha root extract with a standard drug, ranitidine, in various models of gastric ulcer in rats is presented. Indomethacin plus plinduced gastric ulceration model was used in the study.
The creation of ethanolinduced gastric lesions is of multifactorial origin with decrease in gastric mucus amount as one of the involved factors. Five fractions from a successive extraction process ranging from nonpolar to more polar solvents were obtained. Crude extract also significantly reduced volume of gastric secretion, free acidity and. The main chemical components of saudi honey samples composed of winter and summer honeys were identified according to antiulcer and antioxidant activity by using phytochemical and chromatographic analyses. Antiulcer activity, asparagus racemosus, indomethacin. Request pdf antisecretory and antiulcer activity of asparagus racemosus willd.
Jcprc5 336 hepatoprotective activity of herbal preparation hp4 against carbontetrachloride induced hepatotoxicity in mice p. The plant extract exhibited the minimum activity of 28. Exploring indian medicinal plants for antiulcer activity p dharmani, gautam palit division of pharmacology, central drug research institute, lucknow 226 001, india. Ramit singla and vikas jaitak centre for chemical and pharmaceutical sciences, school of basics and applied sciences, central university of punjab, bathinda151001, punjab, india. Preclinical screening of antiulcer activity of asparagus racemosus extract. Antidiarrhoeal potential of asparagus racemosus wild root. Learn more about asparagus racemosus uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain asparagus racemosus. Racemosus procedure of action adaptogen activity a. The ability of extracts to scavenge dpph and superoxide rdaicals was evaluated by in vitro methods. Mohommad shahid department of botany, davpg college, dehradun. Invitro antimutagenic activity of asparagus racemosus. Antifungal activity of asparagus racemosus willd msf. Asparagus racemosus is an important medicinal plant used in the traditional indian system of medicine.
Antiulcer and antioxidant activity of asparagus racemosus willd and. Asparagus racemosus increases sexual drive in women. Gastroduodenal ulcer protective activity of asparagus racemosus. Immunomodulatory and antioxidative potential of asparagus. Reports indicate that the pharmacological activities of a. Comparative study of the antiulcer and antioxidant activity of asparagus racemosus willd shatavari and withania somnifera ashwagandha root extract with a standard drug ranitidine, in various models of gastric ulcer in rats showed reduced ulcer index, volume of gastric secretion, free acidity and total acidity. Exploring indian medicinal plants for antiulcer activity. Asparagus racemosus, a climbing ayurvedic plant, is known for its numerous activities such as hyperlipidemia, hypertension, angina, dysmenorrhea, anxiety disorders, benign prostatic hyperplasia bph, leucorrhoea and urinary tract infections. To study the antisecretory and antiulcer activity of asparagus racemosus willd. Evaluation of the antiulcer activity using the pylorus ligationinduced ulcer model thirty male wistar rats were divided into. Asparagus racemosus is a well known ayurvedic rasayana which prevent ageing, increase longevity, impart immunity, improve mental function, vigor and add. Shatavari was found to relive most of the symptoms in majority of the patients. The root is prescribed in combination with other drugs for the treatment of snakebite and scorpion sting.
Exploring indian medicinal plants for antiulcer activity bioline. Shatavarins containing shatavarin iv with anticancer activity from the roots of asparagus racemosus shankar k. Antiulcer activity of aqueous and ethanolic extracts of. Immunomodulatory activity of asparagus racemosus on systemic. Hemidesmus racemosus, asparagus racemosus, and musa sapientum. Phytochemical screening of ethyl acetate and water extracts was used to detect the. The root of the plant has long been used in the traditional system for various clinical conditions such as antiulcer. The current study evaluated the antimutagenic pottential of methanolic rme and aqueous methanolic extract rae extracted from a. The dried root of ar is used in ayurveda as an antiulcerous and antiinflammatory and has medicinalpharmacological value.
Phytochemical screening of ethyl acetate and water extracts was used to detect the presence of carbohydrates, flavonoids, amino acids, and phenolic acids. A study of ancient classical ayurvedic literature claimed several. Antisecretory and antiulcer activity of asparagus racemosus willd. Antidiarrhoeal potential of asparagus racemosus wild root extracts in laboratory animals n. However, there is no scientific proof justifying the traditional use of asparagus racemosus root in the treatment of diarrhoea.
All books are in clear copy here, and all files are secure so dont worry about it. And asparagus sprengeri regel are also being probably sold in the name of shatavari sharma et al. Asparagus racemosus is a well known mental function, vigor and add vitality to the body and it is also used in nervous disorders, dyspepsia, tumors, inflammation, neuropathy, hepatopathy 3. Venkatesan1, vadivu thiyagarajan1, sathiya narayanan1, arokya arul1, sundararajan raja2, sengodan gurusamy vijaya kumar3, thandavarayan rajarajan3, james britto perianayagam3. Five fractions from a successive extraction process ranging from nonpolar to more polar solvents. Haroon department of physical sciences, faculty of applied sciences, south eastern university of sri lanka, sri lanka abstract plants represent a vast and largely unexplored resource for the discovery of novel metabolites with interesting biological activities. Pharmacological evaluation for antidepressantlike activity. Asparagus racemosus ar is commonly known as shatavari, satawar or satmuli in india and in thailand it is call samsib or raksamsib. Antiulcer and antioxidant activity of asparagus racemosus willd and withania somnifera dunal in rats article in annals of the new york academy of sciences 10561.
The present investigation was aimed at evaluating the antioxidant potential of the alcohol and aqueous extracts of root of asparagus gonoclados baker by in vitro and in vivo methods. It nourishes the female organs, help in balancing the estrogen levels, improves fertility and treats vaginal dryness. Asparagus racemosus, traditionally known as shatavari means who possesses a hundred husbands or acceptable to many. Antiulcer and antioxidant activity of asparagus racemosus willd. Antisecretory and antiulcer activity of asparagus racemosus.
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